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NAPLEX North American Pharmacist Licensure Examination Questions and Answers

Questions 4

LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and NKDA.

His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism and chronic back pain. Post-op day 1, LN’s medication includes Dexamethasone 8mg iv q6h with taper dosing, Ondansetron 4 mg iv q6h prn for N/V, Levothyroxine 0.075 mg po daily, Lisinopril 10 mg po daily, Citalopram 20 mg po daily, Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10 mg suppository daily prn for constipation, Famotidine 20 mg iv q12hr, Metoclopramide 10mg iv q6h, Metformin 500 mg po bid, D51/2NS with 20K at 125 mls/hour and Hydromorphone PCA at 0.2mg/hour of basal rate, demand dose 0.1 mg. lock-out every 6min, one hour limit 2.2 mg/hour. Pertinent morning labs includes serum creatinine 1.4 mg/dl, Mg 1.5 mg/dl, K 5.0 mmol/L, Na 135 mmol/L.

Which of the following medication/s should LN be on to prevent the most common side effect of hydromorphone?

Options:

A.

Ondansetron for N/V

B.

Dexamethasone for N/V

C.

Insulin Sliding scale for hyperglycemia

D.

Docusate sodium / Senna for Constipation

E.

Docusate sodium / Senna for Constipation and ondansetron for N/V

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Questions 5

Which of the following is/are appropriate for pseudomonas skin/soft tissue infections?

Options:

A.

Ertapenem

B.

Cefepime

C.

Ceftaroline

D.

Cefazolin

E.

Vancomycin

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Questions 6

In a study where Rivaroxaban was compared to enoxaparin to find total VTE following HIP replacement surgery, there were 17 total VTE out of 1513 patients in the Rivaraoaban group and 57 total VTE out of 1473 patient in the enoxaparin group. What is the relative risk reduction of using Rivaroxaban over Enoxaparin?

Options:

A.

39%

B.

71%

C.

29%

D.

14%

E.

42%

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Questions 7

What is the Osmolarity in mOsm/L of 40mEq of KCl in 100ml sterile water? (Molecular weight of KCl is 74.5gm/ mol.)?

Options:

A.

400mOsm/L

B.

800mOsm/L

C.

80mOsm/L

D.

200mOsm/L

E.

1600mOsm/L

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Questions 8

A physician orders 300gms of albumin post paracentesis, how many milliliters of 25% albumin do you need to give 300gms?

Options:

A.

300ml

B.

25ml

C.

100ml

D.

1200ml

E.

1000ml

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Questions 9

Which of the following is/are ordinal data?

Options:

A.

NYHA I-IV

B.

Grade of breast cancer

C.

Sex

D.

Improvement Yes/No

E.

Alive or Dead

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Questions 10

Which of the following is/are nominal data?

Options:

A.

Sex

B.

Race

C.

Blood Group

D.

NYHA stages I-IV

E.

Stages of breast cancer

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Questions 11

A Physician orders Dobutamine HCl IV infusion at 5 mcg/kg/min. Dobutamine HCl is available as 500 mg in 250 mL of D5W. The patient weighs 68 kg. Calculate the infusion rate in mL/hr.

Options:

A.

10.2mls/hr

B.

5.2mls/hr

C.

0.17mls/hr

D.

22.4mls/hr

E.

340mls/hr

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Questions 12

A 54-year-old male with a long history of mild persistent asthma on daily fluticasone therapy has been using his albuterol inhaler every day for the past month, and presents requesting a refill. What changes should be made to his current regimen?

Options:

A.

Add ciclesonide to current regimen

B.

Add salmeterol to current regimen

C.

Discontinue fluticasone and instead use salmeterol

D.

Add cromolyn to current regimen

E.

Discontinue fluticasone and add ipratropium to current regimen

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Questions 13

Which of the following would be most appropriate to treat infections associated with stenotrophomonas maltophilia?

Options:

A.

Meropenem

B.

Vancomycin

C.

Ciprofloxacin

D.

Sulfamethoxazole/trimethoprim

E.

Ampicillin

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Questions 14

Which of the following is/are a risk factor for myopathy with statin therapy?

Options:

A.

Hypothyroidism

B.

Vitamin D deficiency

C.

Renal impairment

D.

Hepatic dysfunction

E.

Vitamin C deficiency

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Questions 15

Which of these cardiovascular drug classes is most associated with tachyphylaxis?

Options:

A.

ACE inhibitors

B.

Angiotensin-receptor blockers

C.

Direct renin inhibitors

D.

Calcium channel blockers

E.

Nitrates

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Questions 16

When does the newer chronic kidney disease (CKD) guidelines recommend stopping metformin?

Options:

A.

when the estimated glomerular filtration (eGFR) is <30 mL/min/1.73 m2

B.

when estimated glomerular filtration (eGFR) is <50 mL/min/1.73 m2

C.

when creatinine clearance <30 ml/min

D.

when creatinine clearance <50 ml/min

E.

when serum creatinine is <1.8 mg/dL

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Questions 17

After talking to the physician you find out her labs. Her labs reveled albumin level of 2.1gm/dL, calcium of 7.8mg/dL, glucose 120mg/dL , sodium 138 mmol/L, phenytoin level of 17.8.

Based on the given data which of the following best interprets phenytoin concentration?

Options:

A.

Phenytoin level is with normal limits

B.

Phenytoin level is too high

C.

Phenytoin level is too low

D.

Phenytoin level cannot be determined

E.

Phenytoin level need to be repeated

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Questions 18

What vitamin should the a patient receive to avoid Wernicke- Korsakoff syndrome?

Options:

A.

Thiamine

B.

Cyanocobalamin

C.

Folic Acid

D.

Nicotinic Acid

E.

Magnesium

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Questions 19

Which of these substances is not used as a compounding preservative?

Options:

A.

Benzalkonium chloride

B.

Lecithin

C.

Sodium benzoate

D.

Benzyl alcohol

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Questions 20

What is the active ingredient of the medicine Lyrica?

Options:

A.

Tramadol

B.

Digoxin

C.

Valproate

D.

Pregabalin

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Questions 21

LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and NKDA. His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism and chronic back pain.

Post-op day 1, LN’s medication includes Dexamethasone 8 mg iv q6h with taper dosing, Ondansetron 4 mg iv q6h prn for N/V, Levothyroxine 0.075 mg po daily, Lisinopril 10 mg po daily, Citalopram 20 mg po daily, Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10 mg suppository daily prn for constipation, Famotidine 20 mg iv q12hr, Metoclopramide 10 mg iv q6h, Metformin 500 mg po bid, D51/2NS with 20 K at 125 mls/hour and Hydromorphone PCA at 0.2 mg/hour of basal rate, demand dose 0.1 mg. lock-out every 6 min, one hour limit 2.2 mg/hour. Pertinent morning labs includes serum creatinine 1.4 mg/dl, Mg 1.5 mg/dl, K

5.0 mmol/L, Na 135 mmol/L.

Which of the following medication may cause tardive dyskinesia when given at a higher dose and for a long duration?

Options:

A.

Lisinopril

B.

Dexamethasone

C.

Famotidine

D.

Metoclopramide

E.

Hydromorphone

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Questions 22

LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and NKDA.

His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism and chronic back pain. Post-op day 1, LN’s medication includes Dexamethasone 8mg iv q6h with taper dosing,

Ondansetron 4mg iv q6h prn for N/V, Levothyroxine 0.075mg po daily, Lisinopril 10mg po daily, Citalopram 20mg po daily, Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10mg suppository daily prn for constipation, Famotidine 20mg iv q12hr, Metoclopramide 10mg iv q6h, Metformin 500mg po bid, D51/2NS with 20K at 125mls/hour and Hydromorphone PCA at 0.2mg/hour of basal rate, demand dose 0.1mg. lock-out

every 6min, one hour limit 2.2mg/hour. Pertinent morning labs includes serum creatinine 1.4mg/dl, Mg 1.5mg/ dl, K 5.0mmol/L, Na 135mmol/L.

LN used 5 on-demand bolus doses from the hydromorphone PCA, how much hydromorphone did the patient get in 24 hours?

Options:

A.

10mg

B.

5.3mg

C.

4.8mg

D.

0.5mg

E.

52.8mg

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Questions 23

You receive an order for 40mg/kg/dose of Amoxicillin every 12 hours. Pt’s weight is 18 lbs. You have 250mg/5ml of amoxicillin suspension.

Calculate the total amount in milliliters needed for 10-day supply. Round up your answer to the nearest 1.

Options:

A.

14 mls

B.

132 mls

C.

96 mls

D.

86 mls

E.

36 mls

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Exam Code: NAPLEX
Exam Name: North American Pharmacist Licensure Examination
Last Update: Nov 18, 2024
Questions: 154

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